ARC抗体

Activity-regulated cytoskeleton-associated protein （ARC）in the brain and learning and memory, researchers believe: ARC protein is by strengthening the function of synaptic links in order to save the memory, including learning and memory and emotion. At present, the scientists will also Activity-regulated cytoskeleton-associated protein used to take drugs addiction.
Function : Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
Subunit : Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.
Subcellular Location : Cytoplasm, cytoskeleton. Endosome. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse.
Similarity : Belongs to the ARC/ARG3.1 family.
Database links : UniProtKB/Swiss-Prot: Q7LC44.1
该蛋白与大脑的学习记忆有关，研究人员认为：是ARC蛋白通过加强了突触的联系功能从而储存了这些记忆，包括情感和学习记忆。
目前，科学家也将该蛋白用于吸食毒品成瘾性的研究。