雌激素受体（抗原）

编号：XY-0122P

英文名称ER-Alpha

中文名称雌激素受体  

说 明 书0.5mg  1mg  

多肽活性 多肽

产品来源合成

分    类

偶联蛋白

纯化方法HPLC

产品应用Blocking Peptide of The bs-0122R Antibody

保存条件Store at -20 癈 for one year. The lyophilized powder is stable at room temperature for at least one month and for greater than a year when kept at -20癈. Upon reconstituted, aliquot and store at -20癈 or -80癈. Avoid repeated freeze/thaw cycles.

生 产 商BIOSS

产品介绍background:

牋?Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER Alpha and ER Beta. ER Alpha and ER Beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.